Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2011.418 | A Multicenter, Controlled, Open-label Extension (OLE) Study to Assess the Long-term Safety and Efficacy of Evolocumab (AMG 145) | Dr. LUK Andrea On Yan |
| 2022.162 | A Multicenter, Cross-sectional Study to Characterize the Distribution of Lipoprotein(a) Levels Among Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD) |
Prof. YAN Bryan Ping Yen 甄秉言教授 |
| 2011.416 | A multicenter, double blind, factorial design, phase IV trial to compare the efficacy and safety of Cilostazol long-term treatment with Aspirin in ischemic stroke patients with high risk of cerebral hemorrhage for the prevention of cerebral hemorrhage and cardiovascular events and to compare the preventive effect of Probucol in the same patient group with non-drug use group for the prevention of cardiovascular events | Prof. WONG Lawrence K.S. |
| 2003.327 | A Multicenter, Double-Bind, Double-Dummy, Randomized Study of the Analgesic Efficacy and Safety of Valdecoxib Compared to Diclofenac Sodium in Patients Undergoing Knee Arthroscopy Procedure for Anterior Cruciate Ligament Reconstruction | Dr. Yung S.H. Patrick |
| 2014.227 | A multicenter, double-blind, placebo-controlled, randomised, paralle-group phase 3 study to evaluate the safety and efficacy of masitinib in patients with mild to moderate Alzheimer’s disease | Prof. MOK Vincent Chung Tong |
| 2005.366 | A Multicenter, Double-Blind, Randomized Study to Establish the Clinical Benefit and Safety of Vytorin (Ezetimibe/ Simvastatin Tablet) vs Simvastatin Monotherapy in High-Risk Subjects Presenting With Acute Coronary Syndrome (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial | Prof. YU Cheuk Man |
| 2007.273 | A Multicenter, Double-Blind, Randomized, Placebo and Active Comparator Controlled Dose-Range Finding Study of MK-0893 in Patients with Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control | Dr. Ma Ronald |
| 2005.212 | A Multicenter, Double-Blind, Randomized, Placebo Controlled Study on the Effect of Ultra-Low Dose Transdermal Estradiol (Menostar_ 0.014 mg/day via weekly patch) on the Incidence and Severity of Hot Flushes, Other Menopausal Symptoms and on Well-Being in Postmenopausal Asian Women Over 12 Weeks | Prof. Christopher John Haines |
| 2017.501 | A MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY OF VARLITINIB PLUS CAPECITABINE VERSUS PLACEBO PLUS CAPECITABINE IN PATIENTS WITH ADVANCED OR METASTATIC BILIARY TRACT CANCER AS SECOND-LINE SYSTEMIC THERAPY |
Dr. CHAN Stephen L. 陳林醫生 |
| 2003.020 | A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety and Efficacy of MK-0767 Added to Metformin in Patients with Inadequately Controlled Type 2 Diabetes Mellitus | Dr. Chow Chun Chung Francis |
| 2003.021 | A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety and Efficacy of MK-0767 Added to Sulfonylurea in Patients with Inadequately Controlled Type 2 Diabetes Mellitus | Dr. Chow Chun Chung Francis |
| 2002.283 | A Multicenter, Double-Blind, Randomized, Placebo-controlled Study to Evaluate the Safety and Efficacy of Zoledronic Acid in the Treatment of Osteoporosis in Postmenopausal Women Taking Calcium and Vitamin D | Prof. Leung Ping Chung |
| 2007.372 | A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study of the Safety and Efficacy of A Single Treatment with Two Dose Levels of BOTOXｮ (Botulinum Toxin Type A) Purified Neurotoxin Complex Followed By A Treatment with BOTOXｮ in Patients with Urinary Incontinence due to Neurogenic Detrusor Overactivity | Prof. Chan Chi Kwok |
| 2022.148 | A Multicenter, Double-blind, Randomized, Placebo-Controlled, Phase II/III Study to Evaluate the Efficacy, Safety and Pharmacokinetics of JT001 (VV116) for the Early Treatment of Coronavirus Disease 2019 (COVID-19) in Participants with Mild to Moderate COVID-19 |
Dr. LUK Andrea On Yan 陸安欣 |
| 2016.034 | A Multicenter, Extension Study of the Safety and Efficacy of Multi-dose Intravenous ARC-520 in Combination with Entecavir or Tenofovir in Patients with Chronic Hepatitis B Virus (HBV) Infection |
Prof. CHAN Henry Lik Yuen 陳力元教授 |
| 2011.030 | A multicenter, global, randomized, double-blind study of axitinib plus best supportive care versus placebo plus best supportive care in patients with advanced hepatocellular carcinoma following failure of one prior antiangiogenic therapy | Prof. CHAN Stephen Lam |
| 2012.230 | A Multicenter, International, Randomized, Double-blind, Alendronate-controlled Study to Determine the Efficacy and Safety of Romosozumab in the Treatment of Postmenopausal Women With Osteoporosis | Prof. LEUNG Ping Chung |
| 2012.581 | A Multicenter, International, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy and Safety of Romosozumab Treatment in Postmenopausal Women With Osteoporosis | Prof. LEUNG Ping Chung |
| 2008.209 | A Multicenter, Investigative Trial of the Safety and Efficacy of Extended Administration of Aripiprazole in Combination with Mood Stabilizer for the Treatment of Patients with Bipolar Disorder Experiencing a Manic or Mixed Episode | Prof. Wing Yun Kwok |
| 2019.315 | A multicenter, multinational, prospective, interventional, single-arm, Phase IV study evaluating the clinical efficacy and safety of 26 weeks of treatment with insulin glargine 300 U/mL (Gla-300) in patients with Type 2 diabetes mellitus uncontrolled on basal insulin |
Prof. MA Ronald Ching Wan 馬青雲教授 |
| 2013.167 | A Multicenter, Open-Label Phase 2 Study of the Safety and Activity of Lenvatinib (E7080) in Subjects With KIF5B-RET-Positive Adenocarcinoma of the Lung | Prof. MOK Tony Shu Kam |
| 2013.071 | A Multicenter, Open-label Study to Assess the Long-term Safety, Tolerability, and Efficacy of AMG 145 on LDL-C in Subjects With Severe Familial Hypercholesterolemia | Dr. LUK Andrea On Yan |
| 2023.152 | A Multicenter, Open-Label, First-In-Human, Multiple Expansion Cohort, Phase 1/2 Study to Evaluate the Safety and Efficacy of DR-01 in Adult Subjects with Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas |
Dr. WONG Raymond Siu Ming 王紹明 |
| 2017.446 | A Multicenter, Open-label, Long Term Extension Study to Assess the Safety and Efficacy of Filgotinib in Subjects with Rheumatoid Arthritis |
Prof. TAM Lai Shan 譚麗珊 |
| 2018.334 | A MULTICENTER, OPEN-LABEL, LONG-TERM EXTENSION OF PHASE III STUDIES (BN29552/BN29553) OF CRENEZUMAB IN PATIENTS WITH ALZHEIMER’S DISEASE |
Prof. MOK Vincent Chung Tong 莫仲棠 |
| 2019.387 | A Multicenter, Open-label, Phase I/II Dose Escalation and Expansion Clinical Study to Assess the Safety and Efficacy of MGD013 Monotherapy and in Combination with Brivanib Alaninate (ZL-2301) in Patients with Advanced Liver Cancer | Dr. CHAN Stephen Lam |
| 2005.303 | A Multicenter, Open-Label, Randomized Comparative Study of Tigecycline vs Ceftriaxone Sodium Plus Metronidazole for the Treatment of Hospitalized Subjects with Complicated Intra-Abdominal Infection | Prof. Lai Bo Shan Paul |
| 2020.567 | A Multicenter, Open-label, Randomized Phase 2 Study to Compare the Efficacy and Safety of Lenvatinib in Combination with Ifosfamide and Etoposide versus Ifosfamide and Etoposide in Children, Adolescents and Young Adults with Relapsed or Refractory Osteosarcoma (OLIE) |
Dr. LOONG Herbert Ho Fung 龍浩鋒醫生 |
| 2013.461 | A multicenter, open-label, randomized phase II study to evaluate the efficacy of AUY922 vs pemetrexed or docetaxel in NSCLC patients with EGFR mutations who have progressed on prior EGFR TKI treatment | Prof. MOK Tony Shu Kam |
| 2019.477 | A Multicenter, Open-label, Single-arm, Phase Ib Dose Escalation and Multi-cohort Expansion Clinical Study to Assess the Safety and Antitumor Activity of Niraparib in Combination with MGD013 in Patients with Advanced or Metastatic Solid Tumor Who Failed Prior Treatment | Dr. LOONG Herbert Ho-fung |
| 2008.208 | A Multicenter, Placebo-Controlled, Double-Blind Investigative Extension Trial of the Safety and Efficacy of Aripiprazole in the Treatment of Patients with Bipolar Disorder Experiencing a Manic or Mixed Episode | Prof. Wing Yun Kwok |
| 2025.195 | A Multicenter, Prospective Study of Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios | Prof. LAU James Yun Wong |
| 2014.642 | A multicenter, prospective, double-blind, non-interventional study validating the short-term prediction of preeclampsia / eclampsia / HELLP syndrome in pregnant Asian women with suspected preeclampsia | Prof. LEUNG Tak Yeung |
| 2008.506 | A Multicenter, Randomized, Double Blind, Sham Control, Parallel Arm Trial to Assess Effectiveness and Safety of the Ischemic Stroke System ISS, as an Adjunct to Standard of Care in Subjects with Acute Ischemic Stroke | Assistant Professor LEUNG Thomas Wai Hong |
| 2007.320 | A Multicenter, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Sitagliptin versus Glipizide in Patients with Type 2 Diabetes Mellitus and Chronic Renal Insufficiency Who Have Inadequate Glycemic Control | Dr. Risa Ozaki |
| 2008.323 | A Multicenter, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Sitagliptin versus Glipizide in Patients with Type 2 Diabetes Mellitus and End-Stage Renal Disease Who Are on Dialysis and Who Have Inadequate Glycemic Control | Dr. Yu Alex |
| 2004.370 | A Multicenter, Randomized, Double-Blind Study to Evaluate the Safety of MK-0431 Monotherapy in Patients with Type 2 Diabetes Mellitus and Chronic Renal Insufficiency Who have Inadequate Glycemic Control | Prof. Chan CN Juliana |
| 2007.271 | A Multicenter, Randomized, Double-Blind, | Prof. Brian Tomlinson |
| 2007.282 | A Multicenter, Randomized, Double-Blind, | Prof. Yu Cheuk Man |
| 2005.001 | A Multicenter, Randomized, Double-Blind, Active Controlled Study to Compare the Long-Term Effect (up to 5 Years) of Treatment with LAF237 50 mg Bid to Glimepiride up to 6 mg Daily as Add-On Therapy in Patients with Type 2 Diabetes Inadequately Controlled with Metformin Monotherapy | Dr. Chow Chun Chung Francis |
| 2009.211 | A Multicenter, Randomized, Double-Blind, Active-Controlled Study to Evaluate the Durability of the Efficacy and Safety of Alogliptin Compared to Glipizide When Used in Combination with Metformin in Subjects with Type 2 Diabetes | Dr Tsang Chiu Chi |
| 2009.212 | A Multicenter, Randomized, Double-Blind, Active-Controlled Study to Evaluate the Durability of the Efficacy and Safety of Alogliptin Compared to Glipizide When Used in Combination with Metformin in Subjects with Type 2 Diabetes | Dr. Ozaki Risa |
| 2012.329 | A Multicenter, Randomized, Double-Blind, Active-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of TAK-875 25 mg and 50 mg Compared to Glimepiride When Used in Combination with Metformin in Subjects with Type 2 Diabetes | Dr. OZAKI Risa |
| 2012.314 | A Multicenter, Randomized, Double-Blind, Active-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of TAK-875 25 mg and 50 mg Compared to Glimepiride When Used in Combination with Metformin in Subjects with Type 2 Diabetes | Prof. TOMLINSON Brian |
| 2009.411 | A multicenter, randomized, double-blind, assessor-blind, non-inferiority study comparing the efficacy and safety of once-weekly subcutaneous idrabiotaparinux (SSR126517E) with oral adjusted-dose warfarin in the prevention of stroke and systemic thromboembolic events in patients with atrial fibrillation | Prof. WONG Lawrence Ka Sing |
| 2007.321 | A Multicenter, Randomized, Double-Blind, Controlled Phase 3, Efficacy and Safety Study of Sunitinib (SU011248) in Patients with Advanced/Metastatic Non-Small Cell Lung Cancer Treated with Erlotinib | Prof. Mok S.K. Tony |
| 2007.028 | A Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group, 8-Week Comparative Efficacy and Safety Study of Esomeprazole 20 mg qd Versus Ranitidine 150 mg bid in Patients with An NSAID-Associated Gastric Ulcer When Daily NSAID is Continued | Prof. Chan KL Francis |
| 2015.633 | A multicenter, randomized, double-blind, double-dummy, parallel-group, active-controlled study to evaluate the efficacy and safety of finerenone compared to eplerenone on morbidity and mortality in patients with chronic heart failure and reduced ejection fraction after recent heart failure decompensation and additional risk factors, either type 2 diabetes mellitus or chronic kidney disease or both. |
Dr. LEE Alex Pui Wai 李沛威 |
| 2008.293 | A Multicenter, Randomized, Double-Blind, Parallel Group, 12 Week Study to Evaluate the Efficacy and Safety of MK-0524B (dosed as coadministered MK-0524A and Simvastatin Tablets) Versus Atorvastatin in Patients With Mixed Hyperlipidemia | Dr. So Wing Yee |
| 2010.440 | A multicenter, randomized, double-blind, parallel group, active-controlled study to evaluate the efficacy and safety of LCZ696 compared to enalapril on morbidity and mortality in patients with chronic heart failure and reduced ejection fraction | Associate Professor Yip Wai-Kwok , Gabriel |
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