Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2017.193 | Modelling the Impact of Control Strategies for Tuberculosis Transmission in Hong Kong | Prof. YEOH Eng Kiong |
| 2014.551 | Improving elderly healthcare voucher scheme to incentivise primary care in Hong Kong: How has health service utilization changed | Prof. YEOH Eng Kiong |
| 2020.354 | Tender for the Provision of Services of the Monitoring and Evaluation Study of Kwai Tsing District Health Centre and Sham Shui Po District Health Centre |
Prof. YEOH Eng Kiong 楊永強 |
| 2021.696 | Health Support Pilot Programme for South Asian Ethnic Groups |
Prof. YEOH Eng Kiong 楊永強 |
| 2023.102 | A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Treatment of Physician’s Choice in Patients With Previously Untreated, Locally Advanced, Inoperable or Metastatic Triple-Negative Breast Cancer Whose Tumors Do Not Express PD-L1 or in Patients Previously Treated With Anti-PD-(L)1 Agents in the Early Setting Whose Tumors Do Express PD-L1 | Prof. YEO Winnie Ming Ming |
| 2022.282 | A post-trial access roll-over study to allow access to ribociclib (LEE011) for patients who are on ribociclib treatment in Novartis-sponsored study |
Prof. YEO Winnie 楊明明教授 |
| 2024.137 | A Phase 3, Multicenter, Open-label, Randomized Study to Compare the Efficacy and Safety of MK-2870 Versus Treatment of Physician’s Choice in 3L+ Advanced/Metastatic Gastroesophageal Adenocarcinoma (Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, and Esophageal Adenocarcinoma) | Prof. YEO Winnie |
| 2023.629 | A Phase 3, Randomized, Multi-center, Open-label Study of DB-1303 Versus Investigator’s Choice Chemotherapy in Human Epidermal Growth Factor Receptor 2 (HER2)-low, Hormone Receptor Positive (HR+) Metastatic Breast Cancer Patients whose Disease has Progressed on Endocrine Therapy (ET) (DYNASTY-Breast02) | Prof. YEO Winnie |
| 2022.173 | EPIK-B3: A Phase III, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of alpelisib (BYL719) in combination with nab-paclitaxel in patients with advanced triple negative breast cancer with either phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) mutation or phosphatase and tensin homolog protein (PTEN) loss without PIK3CA mutation |
Prof. YEO Winnie 楊明明教授 |
| 2022.286 | A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician’s Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced, Inoperable, or Metastatic Triple-Negative Breast Cancer, Whose Tumors Express PD-L1 |
Prof. YEO Winnie 楊明明教授 |
| 2024.096 | An Open-label, Randomized Phase 3 Study of MK-2870 as a Single Agent and in Combination with Pembrolizumab Versus Treatment of Physician’s Choice in Participants with HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer | Prof. YEO Winnie |
| 2022.285 | A Phase 1b/3 Study of Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab Alone in Subjects With Previously Untreated Advanced Gastric and Gastroesophageal Junction Cancer With FGFR2b Overexpression (FORTITUDE-102) |
Prof. YEO Winnie 楊明明 |
| 2023.267 | A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Treatment of Physician’s Choice in Patients With Hormone Receptor-Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2−) (HER2 IHC0 or HER2-low [IHC 1+, IHC 2+/ISH−]) Inoperable, Locally Advanced, or Metastatic Breast Cancer and Have Received Endocrine Therapy | Prof. YEO Winnie |
| 2023.269 | A phase IIIb study to characterize the effectiveness and safety of Adjuvant ribociclib in a wide patient population with HR+ HER2-early breast cancer (Adjuvant WIDER) | Prof. YEO Winnie |
| 2021.219 | A Phase 3, Multicenter, 2-Arm Randomized, Open-Label Study of Trastuzumab Deruxtecan in Subjects with HER2-Positive Metastatic and/or Unresectable Gastric or Gastro-Esophageal Junction (GEJ) Adenocarcinoma Subjects who have Progressed on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04) |
Prof. YEO Winnie 楊明明教授 |
| 2022.510 | A Multinational, Multicenter, Non-Interventional, Retrospective, Observational, Real-World Study: Treatment Patterns in Patients with HER2-Positive Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma in East Asia (HER2+ GASTA Study) |
Prof. YEO Winnie 楊明明 |
| 2021.162 | A Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in Subjects with High-Risk HER2-Positive Primary Breast Cancer Who Have Residual Invasive Disease in Breast or Axillary Lymph Nodes Following Neoadjuvant Therapy |
Prof. YEO Winnie 楊明明教授 |
| 2021.563 | A Phase 2 Study of Magrolimab Combination Therapy in Patients With Unresectable, Locally Advanced or Metastatic Triple-Negative Breast Cancer |
Prof. YEO Winnie 楊明明教授 |
| 2016.013 | A Randomized Study to Determine the Efficacy and Tolerability of Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Chinese breast cancer patients. |
Prof. YEO Winnie 楊明明 |
| 2017.169 | Open label single arm study for NEPA [oral fixed-dose combination of 300 mg netupitant and 0.50 mg palonosetron] in Hong Kong oncology patients receiving (neo)-adjuvant chemotherapy treatment consists of adriamycin and cyclophosphamide for breast cancer. | Prof. YEO Winnie |
| 2016.156 | RETROSPECTIVE REVIEW OF TUMOUR CHARACTERISTICS AND OUTCOMES OF BREAST CANCER PATIENTS |
Prof. YEO Winnie 楊明明 |
| 2014.584 | A Phase III randomized, double-blind, placebo-controlled study of LEE011 or placebo in combination with tamoxifen and goserelin or a non-steroidal aromatase inhibitor (NSAI) and goserelin for the treatment of premenopausal women with hormone receptor positive, HER2-negative, advanced breast cancer | Prof. YEO Winnie |
| 2017.478 | A phase III, multicenter, randomized, double-blind, placebo-controlled study to evaluate efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive, HER2-negative, high risk early breast cancer |
Prof. YEO Winnie 楊明明教授 |
| 2014.460 | A Retrospective Study to Assess the Role of Prophylactic Anti-viral Therapies for Patients with CD20+ Lymphoma Receiving Anti-B cell Therapies | Prof. YEO Winnie |
| 2017.356 | China local BRCA testing and exploration of ovarian cancer treatment outcomes of different BRCA status in newly diagnosed epithelial ovarian cancer patients |
Prof. YEO Winnie 楊明明 |
| 2016.435 | A prospective study of circulating and urinary isoflavones and lignans concentration at 60-m after diagnosis and the risk of recurrence and mortality in Chinese women with early-stage breast cancer | Prof. YEO Winnie |
| 2014.596 | A prospective, single-arm, multicenter, uncontrolled, open-label Phase II trial of refametinib (BAY 86-9766) in combination with sorafenib as first line treatment in patients with RAS mutant Hepatocellular Carcinoma (HCC) | Prof. YEO Winnie |
| 2015.184 | A 60-m prospective study of long-term intake of dietary isoflavones and lignans on the risk of recurrence and mortality in Chinese women with early-stage breast cancer | Prof. YEO Winnie |
| 2015.507 | A Randomized Open-Label Phase III Study of Single Agent Pembrolizumab versus Single Agent Chemotherapy per Physician’s Choice for Metastatic Triple Negative Breast Cancer (mTNBC) – (KEYNOTE-119) |
Prof. YEO Winnie 楊明明 |
| 2017.072 | A Prospective Study on the Role of Pharmacogenomic Study in Association with Chemotherapy-Induced Nausea and Vomiting | Prof. YEO Winnie |
| 2015.696 | RETROSPECTIVE REVIEW OF EFFICACY AND TOLERABILITY OF T-DM1 IN ADVANCED HER2+ BREAST CANCER |
Prof. YEO Winnie 楊明明 |
| 2014.529 | A randomised controlled trial to assess the effectiveness and cost-effectiveness of acupuncture in the management of chemotherapy-induced peripheral neuropathy | Prof. YEO Winnie |
| 2017.320 | A Randomized, Multicenter, Open-Label, Phase 3 Study of Nivolumab plus Ipilimumab or Nivolumab in Combination with Oxaliplatin plus Fluoropyrimidine versus Oxaliplatin plus Fluoropyrimidine in Subjects with Previously Untreated Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer |
Prof. YEO Winnie 楊明明 |
| 2016.290 | A Phase III open-label, multicenter trial of avelumab (MSB0010718C) as a third-line treatment of unresectable, recurrent, or metastatic gastric or gastroesophageal junction adenocarcinoma |
Prof. YEO Winnie 楊明明 |
| 2015.689 | A Randomized, Multi-center Phase III Study of Nivolumab versus Sorafenib as First-Line Treatment in Patients with Advanced Hepatocellular Carcinoma |
Prof. YEO Winnie 楊明明 |
| 2017.262 | A comparison of 24-h dietary recalls and mobile phone food record among Hong Kong Chinese women with early-stage breast cancer |
Prof. YEO Winnie 楊明明 |
| 2016.010 | Cancer Health Literacy among Chinese cancer patients in Hong Kong | Prof. YEO Winnie |
| 2002.230 | "HERA: A Randomized Three-arm Multi-centre Comparison of 1 Year and 2 Years of Herceptin Versus No Herceptin in Women with HER2-positive Primary Breast Cancer Who Have Completed Adjuvant Chemotherapy" | Prof. YEO Winnie |
| 2009.202 | A Randomized, Double-blind, Multi-center Phase III Study of Brivanib plus Best Supportive Care (BSC) versus Placebo plus BSC in Subjects with Advanced Hepatocellular Carcinoma (HCC) who have Failed or are Intolerant to Sorafenib | Professor Yeo Winnie |
| 2008.294 | A Multicenter Phase III Randomized Trial of Adjuvant Therapy for Patients with HER2-Positive Node-Positive or High Risk Node-Negative Breast Cancer Comparing Chemotherapy Plus Trastuzumab with Chemotherapy Plus Trastuzumab Plus Bevacizumab | Prof Yeo Winnie |
| 2009.376 | A Randomized, Double-blind, Multi-centre Phase III Study of Brivanib versus Sorafenib as First-line Treatment in Patients with Advanced Hepatocellular Carcinoma: The BRISK FL Study | Professor Yeo Winnie |
| 2009.360 | A randomised Phase III clinical study of bevacizumab plus capecitabine vs. bevacizumab alone as maintenance therapy in patients with HER2-negative metastatic breast cancer that has not progressed during first-line docetaxel plus bevacizumab therapy | Prof. YEO Winnie |
| 2010.235 | Prospective study of soy intake and breast cancer prognosis in Chinese breast cancer survivors | Prof. YEO Winnie |
| 2008.395 | Phase I/II Study of Temsirolimus (Torisel) as Novel Therapeutic Drug for Patients with Unresectable Hepatocellular Carcinoma (HCC) - A Correlative Study with Stathmin Over-expression | Prof. YEO Winnie |
| 2010.601 | LUX-Breast 2: An open label, phase II trial of BIBW 2992 (afatinib) in patients with metastatic HER2-overexpressing breast cancer failing HER2-targeted treatment in the neoadjuvant and/or adjuvant treatment setting | Prof. YEO Winnie |
| 2008.235 | A Multinational, Randomized, Open-Label, Phase 3 Study of Sunitinib Malate versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma | Professor Yeo Winnie |
| 2008.284 | Premature Postmenopausal Symptoms Affecting the Quality of Life of Younger Breast Cancer Survivors in Hong Kong | Prof. YEO Winnie |
| 9406(S) | A Prospective Randomized Phase III Study Comparing the Combination of Cisplatin, Doxorubicin, Interferon-Alpha-2B and 5-Fluorouracil to Doxorubicin Alone in the Treatment of Inoperable Hepatocellular Carcinoma | Prof. YEO Winnie |
| 2007.095 | Phase I/II Study of Paclitaxel/ Carboplatin/ RAD001 as First Line Therapy for Advanced Adenocarcinoma of the Stomach | Prof. YEO Winnie |
| 2012.145 | A PHASE III PROSPECTIVE, TWO-COHORT NON-RANDOMIZED, MULTI-CENTRE, MULTINATIONAL, OPEN LABEL STUDY TO ASSESS THE SAFETY OF ASSISTED- AND SELF-ADMINISTERED SUBCUTANEOUS TRASTUZUMAB AS THERAPY IN PATIENTS WITH OPERABLE HER2-POSITIVE EARLY BREAST CANCER [SafeHer Study] | Prof. YEO Winnie |
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