Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2013.161 | Xenobiotic transporter ABCG2: Regulatory role in the initiation and progression of colorectal cancer | Professor To Kin Wah |
| 2011.034 | Exploiting regulation of the drug transporter ABCG2 for personalized treatment with the HMG-CoA reductase inhibitors (Statins) | Prof To Kin Wah |
| 2011.155 | Novel prognostic biomarkers for predicting response to chemotherapy in colorectal cancer | Professor To Kin Wah |
| 2008.193 | A Cross Sectional Study of Prevalence of Sleep Disordered Breathing in Patients on HAART in a HIV Clinic in Hong Kong | Dr To Kin Wang |
| 2013.689 | A cross over case control study using a vibration positional device for treatment of position dependent obstructive sleep apnea | Dr. TO Kin Wang |
| 2012.037 | Comparison of Nasal Positive End Expiratory Pressure valve to dental device as an alternative treatment for OSA | Dr. To Kin Wang |
| 2019.025 | A validation study of a portable monitoring device for diagnosing obstructive sleep apnea in patients with co-existing medical illnesses | Dr. TO Kin Wang |
| 2020.034 | Prospective study to evaluate Stretococcus pneumoniae serotype prevalence in community acquired pneumonia in Hong Kong using a urinary kit |
Dr. TO Kin Wang 杜建宏 |
| 2018.478 | Situation of idiopathic pulmonary fibrosis in Hong Kong --- a 5 year retrospective epidemiology study |
Dr. TO Kin Wang 杜建宏 |
| 2014.556 | Application of GeneXpert on bronchoscopic samples in the clinical management of patients suspicious of Tuberculosis | Dr. TO Kin Wang |
| 2016.661 | Validation of a novel device for screening patients with symptoms of obstructive sleep apnea |
Dr. TO Kin Wang 杜建宏 |
| 2016.737 | Mortality among Tuberculosis patients in Hong Kong |
Dr. TO Kin Wang 杜建宏 |
| 2018.159 | Endoscopic retrograde cholangiopancreatography (ERCP) in older patients: is age a risk factor for complications? |
Dr. TO Tsz Yan 杜芷茵 |
| 2022.354 | An investigation of air dispersion pattern and the environmental influence of open airway suction in general ward setting and identification of a practical enclosure device for open airway suction in general ward. |
Ms. TO YUK LING 杜玉玲 |
| 2021.127 | The effect of culturally-adapted music therapy on preoperative anxiety, acute postoperative pain and haemodynamic readings among women with breast cancer receiving mastectomy in Nigeria: A randomised controlled trial | Ms. TOLA Yetunde Oluwafunmilayo |
| 2011.341 | A Single-Dose, Randomized, Double-Blind, Parallel-Group, Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BIIB023 in Chinese, Japanese, and Caucasian Adult Healthy Volunteers | Professor Tomlinson Brian |
| 2009.156 | Prevalence, Treatment Patterns & Resource Use in Patients with Mixed Dyslipidemia Using Lipid Lowering Agents | Prof Tomlinson Brian |
| 2011.473 | Effect of a multi-herb product on plasma lipids levels in Chinese patients with dyslipidaemia | Prof Tomlinson Brian |
| 2008.151 | Investigation on the Pharmacogenetics of Medications Used in Pharmacokinetic Trials | MD Tomlinson Brian |
| 2012.340 | Retrospective case review of patients during diagnosed as having rhabdomyolysis in the Prince of Wales Hospital | Prof. TOMLINSON Brian |
| 2011.472 | Pharmacogenomics of Niacin in Patients with Erectile Dysfunction and Dyslipidaemia - a Follow-on Study | Prof Tomlinson Brian |
| 2008.572 | The combined effects of drug transporter pharmacogenetics and drug interactions on the pharmacokinetics of statins in Chinese subjects-Simvastatin pharmacokinetic study | Professor Tomlinson Brian |
| 2011.002 | Does the plasma Cholesterol level Affect the Expression of drug Transporters? | Prof Tomlinson Brian |
| 2013.676 | Investigation of cases of drug/chemical toxicity, adverse drug reactions and interactions | Prof. TOMLINSON Brian |
| 2015.115 | The impact of Illness Representations on illness management in patients with Familial Hypercholesterolemia |
Prof. TOMLINSON Brian 湯寧信 |
| 2014.516 | Comparison of serum thromboxane B2 and platelet function testing with the Multiplate® device as measures of aspirin resistance in Hong Kong Chinese patients with increased cardiovascular risk with stable coronary heart disease or peripheral artery disease | Prof. TOMLINSON Brian |
| 2015.116 | Health care resource utilization analysis of paliperidone palmitate in the treatment of schizophrenia in the public health care sector of Hong Kong |
Prof. TOMLINSON Brian 湯寧信醫生 |
| 2015.429 | Cost effectiveness of Dapagliflozin for the treatment of Type 2 Diabetes Mellitus in Hong Kong |
Prof. TOMLINSON Brian 湯寧信醫生 |
| 2015.448 | Retrospective pharmacogenetic analysis of dose requirement in patients on long-term stable warfarin treatment |
Prof. TOMLINSON Brian 湯寧信醫生 |
| 2010.512 | A Randomized, Open-label, Single-dose, Two-period, Crossover Study to Demonstrate the Bioequivalence of the Fixed Dose Combination (FDC) of lamivudine and adefovir dipivoxil (100mg/10mg) to Heptodin_ (100mg) and Hepsera_ (10mg) | Professor Tomlinson Brian |
| 2009.159 | A Phase III Randomized, Placebo-Controlled Clinical Trial to Study the Safety and Efficacy of the Addition of Sitagliptin (MK-0431) in Patients with Type 2 Diabetes Mellitus who Have Inadequate Glycemic Control on Combination Therapy with Metformin and Pioglitazone | Prof. Tomlinson Brian |
| 2012.331 | A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Additional LDL-Cholesterol Reduction on Major Cardiovascular Events When AMG 145 is Used in Combination With Statin Therapy In Patients with Clinically Evident Cardiovascular Disease | Professor Tomlinson Brian |
| 2011.271 | A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate Tolerablility and Efficacy of AMG 145 on LDL-C in Subjects with Heterozygous Familial Hypercholesterolemia | Professor Tomlinson Brian |
| 2010.399 | Phase I, open label, randomized study to examine the pharmacokinetics, safety and tolerability of different oral doses of TMC435 after single and repeated dosing in healthy Chinese subjects | Prof. Tomlinson Brian |
| 2010.163 | Pharmacogenomics of nicotinic acid with laropiprant in Hong Kong Chinese patients with dyslipidemia | Prof Tomlinson Brian |
| 2009.045 | The Combined Effects of Drug Transporter Pharmacogenetics and Drug Interactions on the Pharmacokinetics of Statins in Chinese Subjects-Rosuvastatin Pharmacokinetics Study | Professor Tomlinson Brian |
| 2009.044 | Pilot Study on the Use of Different Adhesive Devices for Stratum Corneum Collection in Dermatopharmacokinetic Studies | Prof. Tomlinson Brian |
| 2012.276 | A Double-blind, Randomized, Multicenter Study to Evaluate Safety and Efficacy of AMG 145, Compared With Ezetimibe, in Hypercholesterolemic Subjects Unable to Tolerate an Effective Dose of a HMG-CoA Reductase Inhibitor | Professor Tomlinson Brian |
| 2011.390 | Pharmacokinetic interaction between rosuvastatin and telmisartan | Prof. TOMLINSON Brian |
| 2010.200 | A Randomized, Double-Blind, Placebo-controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Canagliflozin Compared With Placebo in the Treatment of Older Subjects With Type 2 Diabetes Mellitus Inadequately Controlled on Glucose Lowering Therapy | Prof. Tomlinson Brian |
| 2010.322 | Pharmacogenomics of nicotinic acid with laropiprant in Hong Kong Chinese patients with dyslipidemia | Prof Tomlinson Brian |
| 2010.480 | SAVOR Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus A Multicenter, Randomised, Double-Blind, Placebo-Controlled Phase IV Trial to Evaluate the Effect of Saxagliptin on the Incidence of Cardiovascular Death, Myocardial Infarction or Ischaemic Stroke in Patients with Type 2 Diabetes | Professor Tomlinson Brian |
| 2012.269 | A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate Safety, Tolerability and Efficacy of AMG 145 on LDL-C in Subjects with Heterozygous Familial Hypercholesterolemia | Professor Tomlinson Brian |
| 2006.147 | Pharmacogenetics of HMG Co-A Reductase Inhibitors in Chinese Patients with Hyperlipidaemia: A Combined Pharmacodynamic Pharmacokinetic Approach | Prof. TOMLINSON Brian |
| 2010.600 | An Open Label, Randomized, Cross-Over Study to Investigate the Single Dose Bioequivalence of Lamotrigine Dispersible/Chewable Tablets (5mg) Compared to Lamotrigine Compressed/Standard Tablets (25mg) in Chinese Healthy Male Subjects. | Professor Tomlinson Brian |
| 2011.616 | An Open Label, Pharmacogenetic study of Bisoprolol Treatment in Patients with Uncontrolled Essential Hypertension | Professor Tomlinson Brian |
| 2009.261 | TECOS: A Randomized, Placebo Controlled Clinical Trial to Evaluate Cardiovascular Outcomes after Treatment with Sitagliptin in Patients with Type 2 Diabetes Mellitus and Inadequate Glycemic Control | Prof. TOMLINSON Brian |
| 2013.052 | Pharmacogenomics of anti-hypertensive treatment in Chinese, from unpredictable response to personalized medicine | Prof Tomlinson Brian |
| 2011.151 | A Phase III Multicenter, Double-Blind, Crossover Design Study to Evaluate Lipid-Altering Efficacy and Safety of Extended- Release Niacin/Laropiprant/Simvastatin Combination Tablet in Patients with Primary Hypercholesterolemia or Mixed Dyslipidemia | Prof. Tomlinson Brian |
| 2011.521 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Followed by an Open-Label Continuation Period to Assess the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients with Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol | Prof. TOMLINSON Brian |
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