Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2018.188 | Machine Learning Model to Predict Clinical Events in Patients with History of Peptic Ulcer Bleeding | Dr. WONG Grace Lai Hung |
| 2020.509 | A Phase 2a, Multicenter, Single-Blind, Placebo-Controlled, Multiple Cohort Study Evaluating ABI-H2158-Containing Regimens in Chronic Hepatitis B Infection |
Prof Wong Grace Lai Hung 黃麗虹 |
| 2020.615 | Evaluation of AFP, AFP-L3, PIVKA-II and GALAD Score (Gender, Age, AFP-L3, AFP, DCP/PIVKA-II) for risk assessment of Hepatocellular Carcinoma (HCC) | Prof. WONG Grace Lai Hung |
| 2020.074 | Secular trend of coronavirus infections - a retrospective observational cohort study |
Dr. WONG Grace Lai Hung 黃麗虹 |
| 2019.260 | AN OBSERVER BLIND, RANDOMIZED STUDY WITH AN OPEN LABEL PART TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SUBCUTANEOUS ADMINISTRATION OF RO7191863 WITH MULTIPLE DOSES AND DIFFERENT REGIMENS IN VIROLOGICALLY SUPPRESSED PATIENTS WITH CHRONIC HEPATITIS B INFECTION |
Prof. WONG Grace Lai Hung 陳力元 |
| 2020.459 | Elimination of chronic hepatitis B in Hong Kong – to meet the WHO goals |
Prof. WONG Grace Lai Hung 黃麗虹 |
| 2020.310 | A Phase 2a, Multicenter, Single-Blind, Placebo-Controlled Study Evaluating Treatment Intensification with ABI-H0731 in Subjects with Chronic Hepatitis B Infection on Nucleos(t)ide Reverse Transcriptase Inhibitors | Prof. WONG Grace Lai Hung |
| 2014.690 | Secular trend of etiologies of hepatocellular carcinoma (HCC) - a retrospective observational cohort study | Dr. WONG Grace Lai Hung |
| 2014.537 | Residual intrahepatic viral replication and the development of hepatocellular carcinoma in patients with chronic hepatitis B on oral nucleos(t)ide analogues: A longitudinal study with serial serum hepatitis B virus RNA measurement | Dr. WONG Grace Lai Hung |
| 2015.121 | Secular trend of etiologies of hepatic events - a retrospective observational cohort study |
Dr. WONG Grace Lai Hung 黃麗虹 |
| 2016.224 | Impact of long-term tenofovir disoproxil fumarate (TDF) treatment on the risk of HCC in patients with chronic hepatitis B related cirrhosis |
Dr. WONG Grace Lai Hung 黃麗虹 |
| 2017.214 | Risk of hepatocellular carcinoma in patients with chronic hepatitis B achieved complete viral suppression – role of on-treatment hepatitis B surface/core-related antigen (HBsAg/HBcrAg) levels |
Dr. WONG Grace Lai Hung 黃麗虹 |
| 2015.089 | Dynamic change of LSM-HCC score and enhanced liver fibrosis (ELF) score to predict hepatocellular carcinoma (HCC) in chronic hepatitis B patients receiving antiviral treatment |
Prof. WONG Grace Lai Hung 黃麗虹 |
| 2017.421 | Secular trend of deaths - a retrospective observational cohort study |
Dr. WONG Grace Lai Hung 黃麗虹 |
| 2017.419 | Prevention of recurrent ulcer bleeding in patients with idiopathic gastroduodenal ulcer: a double-blind randomised trial on misoprostol combined with lansoprazole versus lansoprazole alone (NRT_MISO Study) |
Dr. WONG Grace Lai Hung 黃麗虹 |
| 2016.595 | Secular trend of viral hepatitis - a retrospective observational cohort study |
Dr. WONG Grace Lai Hung 黃麗虹 |
| 2016.005 | REAL-C: Real-World Evidence from the Asia Liver Consortium for HCV |
Dr. WONG Grace Lai Hung 黃麗虹 |
| 2016.140 | Dynamic change of liver and spleen stiffness measurement (LSSM) to predict incident varices in cirrhotic patients |
Dr. WONG Grace Lai Hung 黃麗虹 |
| 2021.517 | A Randomized, Open-Label, Multicenter Study Investigating AB-729, Nucleos(t)ide Analogue and Pegylated Interferon Alfa-2a Treatment in Subjects with Chronic Hepatitis B Infection |
Prof. WONG Grace Lai Hung 黃麗虹 |
| 2023.268 | A Phase 2 Multicenter, Randomized, Open-label Study to Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and Pegylated Interferon Alpha (PEG-IFNα) Combination Therapy for the Treatment of Chronic Hepatitis B Virus (HBV) Infection | Prof. WONG Grace Lai Hung |
| 2021.427 | A Phase 2a, Open-Label Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB) |
Prof. WONG Grace Lai Hung 黃麗虹教授 |
| 2024.058 | A Double-Blind, Randomized, Placebo-Controlled, Single and Multiple Dose Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AB-101, an Oral PD-L1 Inhibitor, in Healthy Subjects and Subjects with Chronic HBV Infection | Prof. WONG Grace Lai Hung |
| 2024.057 | A Long-Term Follow-up Study for Subjects with Chronic Hepatitis B Previously Treated with Imdusiran (AB-729) | Prof. WONG Grace Lai Hung |
| 2023.344 | A Phase 1/2 Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BW-20507 in Healthy Subjects and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Subjects with Chronic HBV Infection | Prof. WONG Grace Lai Hung |
| 2021.112 | A Phase 2 Multicenter, Randomized, Open-label Study to Investigate the Safety and Efficacy of BRII-835 (VIR-2218) and BRII-179 (VBI-2601) Combination Therapy for the Treatment of Chronic Hepatitis B Virus (HBV) Infection | Prof. WONG Grace Lai Hung |
| 2023.039 | A Phase 1b Multi-Center, Open-Label, Dose-Escalation, Prime and Boost Vaccination Evaluation of Two Chimpanzee Adenoviral Vectors in Adult Participants With Chronic HBV Infection Who Are Currently Receiving HBV Nucleos(t)ide Reverse Transcriptase Inhibitors | Prof. WONG Grace Lai Hung |
| 2023.265 | A Phase 1a/1b Study to Evaluate the Safety and Tolerability of Repeated Doses of Nonreplicating Arenavirus Vector Therapeutic Vaccines GS-2829 and GS-6779 in Healthy Participants and Participants With Chronic Hepatitis B (CHB) |
Prof. WONG Grace Lai Hung Lai Hung Wong |
| 2021.106 | Prospective evaluation of a fast-track treatment pathway for patients with chronic hepatitis B under primary care |
Prof. WONG Grace Lai Hung 黃麗虹 |
| 2023.273 | A PHASE I STUDY TO INVESTIGATE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF RO7565020 IN HEALTHY PARTICIPANTS AND IN PARTICIPANTS WITH CHRONIC HEPATITIS B VIRUS INFECTION |
Prof. WONG Grace Lai Hung 35053759 |
| 2022.552 | Phase 3 Multicenter, Randomized, Double-Blind, Study to Assess the Efficacy and Safety of Treatment with Bepirovirsen in Nucleos(t)ide Analogue-treated Participants with Chronic Hepatitis B Virus (B-Well 1) |
Prof. WONG Grace Lai Hung 黃麗虹 |
| 2024.002 | A Phase 2a, Open-Label Multiple Dose Study Evaluating the Safety, Tolerability, and Pharmacodynamics of Imdusiran (AB-729) in Combination with Intermittent Dosing of Durvalumab, a PD-L1 Monoclonal Antibody, in Subjects with Chronic HBV Infection | Prof. Wong Grace Lai Hung |
| 2022.678 | A Phase 2 Study Evaluating the Efficacy and Safety of VIR-3434 and/or VIR-2218 Containing Regimens in Participants with Chronic Hepatitis B Infection (STRIVE) | Prof. WONG Grace Lai Hung |
| 2022.676 | A Phase 2 Study Evaluating the Efficacy and Safety of VIR-3434 and/or VIR-2218 Containing Regimens in HBeAg-negative Participants with Low Viral Burden of Chronic Hepatitis B Infection (THRIVE) | Prof. WONG Grace Lai Hung |
| 2022.653 | A Phase 1/2a, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of BJT-778 in Healthy Volunteers and in Subjects with Chronic Hepatitis B Infection, Including Subjects with Chronic Hepatitis D Infection | Prof. WONG Grace Lai Hung |
| 2023.684 | A phase II clinical study to evaluate the safety, efficacy, and pharmacokinetics of RBD1016 injection in participants with chronic hepatitis B | Prof. WONG Grace Lai Hung |
| 2022.601 | Real-World Data to Assess HCV Patients Treated with SOF/VEL without RBV |
Prof Wong Grace Lai Hung 黃麗虹教授 |
| 2021.297 | A Phase 2 Study to Evaluate the Safety, Tolerability, and Efficacy of Regimens Conatining VIR-2218, VIR-3434, and/or PEG-IFNa in Subjects with Chronic Hepatitis B Virus Infection |
Prof. WONG Grace Lai Hung 黃麗虹 |
| 2023.151 | A phase 2b, open-label study to evaluate the efficacy, safety, tolerability, immunogenicity and treatment regimens of VTP-300 combined with low-dose nivolumab in Chronic Hepatitis B Infection |
Prof. WONG Grace Lai Hung Grace LH Wong |
| 2022.324 | Chronic kidney disease progression in chronic hepatitis B patients on tenofovir alafenamide (TAF) versus entecavir |
Prof. WONG Grace Lai Hung 黃麗虹 |
| 2023.200 | A Phase 1, Double-Blind, Randomized, Placebo-Controlled, First-in-Human Study of Orally Administered ALG-000184 to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single-Ascending Doses (Part 1) and Multiple-Ascending Doses in Healthy Volunteers (Part 2), and Multiple Doses in Subjects with Chronic Hepatitis B (Part 3) |
Prof. WONG Grace Lai Hung Grace LH Wong |
| 2022.480 | A PHASE II, RANDOMISED, ADAPTIVE, OPEN-LABEL PLATFORM TRIAL TO EVALUATE EFFICACY AND SAFETY OF MULTIPLE COMBINATION THERAPIES IN PARTICIPANTS WITH CHRONIC HEPATITIS B |
Prof. WONG Grace Lai Hung 黃麗虹教授 |
| 2022.509 | Sodium-glucose co-transporter-2 inhibitor (SGLT2i) to prevent of liver complications in patients with chronic hepatitis B and diabetes mellitus: a double-blind, randomised, placebo-controlled trial |
Prof. WONG Grace Lai Hung 黃麗虹教授 |
| 2009.169 | Prevalence of Advanced Fibrosis among Chronic Hepatitis C Patients in Hong Kong | Prof. WONG Grace Lai Hung |
| 2013.118 | Evaluation of clinical outcomes in patients with viral hepatitis B or C - a retrospective observational cohort study | Dr. WONG Grace Lai Hung |
| 2024.313 | A Phase 1b Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Cavrotolimod Alone and in Combinations in Subjects with Chronic Hepatitis B Infection |
Prof. WONG Grace Lai Hung Wai Sun Vincent Wong |
| 2024.361 | Overcoming Inequalities in Health to Eliminate Hepatitis – Real-World Evidence from a Territory-Wide Cohort |
Prof. WONG Grace Lai Hung Lai Hung Grace Wong |
| 2024.007 | Secular trend of chronic liver diseases - a retrospective observational cohort study | Prof. WONG Grace |
| 2023.312 | An Open-Label Phase 1b Study Evaluating the Safety, Tolerability, Immunogenicity and Antiviral Activity of Multiple Doses of CLB-3000 in Subjects with Chronic Hepatitis B | Prof. WONG Grace |
| 2008.073 | Computed Tomography Antiography and Venography in Place of Catheter Angiography for Acute Spontaneous Non-Hypertensive Intracerebral Haemorrhage | Dr. Wong George Kwok-chu |
| 2007.436 | Co-Operative Study on Brain Injury Depolarisations (COSBID): (Traumatic and Ischaemic Injury to the Human Brain) | Dr. Wong George Kwok-chu |
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