Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2012.290 | Effect of probucol on reducing cardiovascular risk factors in Chinese patients with heterozygous familial hypercholesterolaemia | Prof Tomlinson Brian |
| 2013.052 | Pharmacogenomics of anti-hypertensive treatment in Chinese, from unpredictable response to personalized medicine | Prof Tomlinson Brian |
| 2007.495 | Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation, Repeated Dose Study on the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AVE5026 (10, 20 and 60 mg) Given Once Daily as Subcutaneous Injections in Healthy Young Male Chinese Subjects | MD Tomlinson Brian |
| 2008.153 | A 2 year extension to: A 76-week, Worldwide, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Assess the Tolerability and Efficacy of Anacetrapib When Added to Ongoing Therapy with a Statin in Patients with Coronary Heart Disease (CHD) or CHD Risk-Equivalent Disease: Reversal period extended from 12 weeks to 1-year | Professor Tomlinson Brian |
| 2008.152 | Evaluation of Bilberry (Vaccinium Myrtillus) Supplementation on Biomarkers of Glycaemic Control, Antioxidant Status, Inflammation and Coronary Heart Disease Risk in Type 2 Diabetic Subjects | Prof Tomlinson Brian |
| 2012.314 | A Multicenter, Randomized, Double-Blind, Active-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of TAK-875 25 mg and 50 mg Compared to Glimepiride When Used in Combination with Metformin in Subjects with Type 2 Diabetes | Prof. TOMLINSON Brian |
| 2012.330 | A randomized, double-blind, crossover study to assess the effects of LCZ696 and valsartan in Asian patients with salt-sensitive hypertension | Prof. Tomlinson Brian |
| 2012.331 | A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Additional LDL-Cholesterol Reduction on Major Cardiovascular Events When AMG 145 is Used in Combination With Statin Therapy In Patients with Clinically Evident Cardiovascular Disease | Professor Tomlinson Brian |
| 2006.147 | Pharmacogenetics of HMG Co-A Reductase Inhibitors in Chinese Patients with Hyperlipidaemia: A Combined Pharmacodynamic Pharmacokinetic Approach | Prof. TOMLINSON Brian |
| 2009.159 | A Phase III Randomized, Placebo-Controlled Clinical Trial to Study the Safety and Efficacy of the Addition of Sitagliptin (MK-0431) in Patients with Type 2 Diabetes Mellitus who Have Inadequate Glycemic Control on Combination Therapy with Metformin and Pioglitazone | Prof. Tomlinson Brian |
| 2012.340 | Retrospective case review of patients during diagnosed as having rhabdomyolysis in the Prince of Wales Hospital | Prof. TOMLINSON Brian |
| 2011.341 | A Single-Dose, Randomized, Double-Blind, Parallel-Group, Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BIIB023 in Chinese, Japanese, and Caucasian Adult Healthy Volunteers | Professor Tomlinson Brian |
| 2011.002 | Does the plasma Cholesterol level Affect the Expression of drug Transporters? | Prof Tomlinson Brian |
| 2009.156 | Prevalence, Treatment Patterns & Resource Use in Patients with Mixed Dyslipidemia Using Lipid Lowering Agents | Prof Tomlinson Brian |
| 2011.473 | Effect of a multi-herb product on plasma lipids levels in Chinese patients with dyslipidaemia | Prof Tomlinson Brian |
| 2008.572 | The combined effects of drug transporter pharmacogenetics and drug interactions on the pharmacokinetics of statins in Chinese subjects-Simvastatin pharmacokinetic study | Professor Tomlinson Brian |
| 2011.472 | Pharmacogenomics of Niacin in Patients with Erectile Dysfunction and Dyslipidaemia - a Follow-on Study | Prof Tomlinson Brian |
| 2013.676 | Investigation of cases of drug/chemical toxicity, adverse drug reactions and interactions | Prof. TOMLINSON Brian |
| 2008.151 | Investigation on the Pharmacogenetics of Medications Used in Pharmacokinetic Trials | MD Tomlinson Brian |
| 2015.429 | Cost effectiveness of Dapagliflozin for the treatment of Type 2 Diabetes Mellitus in Hong Kong |
Prof. TOMLINSON Brian 湯寧信醫生 |
| 2015.115 | The impact of Illness Representations on illness management in patients with Familial Hypercholesterolemia |
Prof. TOMLINSON Brian 湯寧信 |
| 2014.516 | Comparison of serum thromboxane B2 and platelet function testing with the Multiplate® device as measures of aspirin resistance in Hong Kong Chinese patients with increased cardiovascular risk with stable coronary heart disease or peripheral artery disease | Prof. TOMLINSON Brian |
| 2015.116 | Health care resource utilization analysis of paliperidone palmitate in the treatment of schizophrenia in the public health care sector of Hong Kong |
Prof. TOMLINSON Brian 湯寧信醫生 |
| 2015.448 | Retrospective pharmacogenetic analysis of dose requirement in patients on long-term stable warfarin treatment |
Prof. TOMLINSON Brian 湯寧信醫生 |
| 2021.127 | The effect of culturally-adapted music therapy on preoperative anxiety, acute postoperative pain and haemodynamic readings among women with breast cancer receiving mastectomy in Nigeria: A randomised controlled trial | Ms. TOLA Yetunde Oluwafunmilayo |
| 2022.354 | An investigation of air dispersion pattern and the environmental influence of open airway suction in general ward setting and identification of a practical enclosure device for open airway suction in general ward. |
Ms. TO YUK LING 杜玉玲 |
| 2018.159 | Endoscopic retrograde cholangiopancreatography (ERCP) in older patients: is age a risk factor for complications? |
Dr. TO Tsz Yan 杜芷茵 |
| 2019.025 | A validation study of a portable monitoring device for diagnosing obstructive sleep apnea in patients with co-existing medical illnesses | Dr. TO Kin Wang |
| 2020.034 | Prospective study to evaluate Stretococcus pneumoniae serotype prevalence in community acquired pneumonia in Hong Kong using a urinary kit |
Dr. TO Kin Wang 杜建宏 |
| 2018.478 | Situation of idiopathic pulmonary fibrosis in Hong Kong --- a 5 year retrospective epidemiology study |
Dr. TO Kin Wang 杜建宏 |
| 2012.037 | Comparison of Nasal Positive End Expiratory Pressure valve to dental device as an alternative treatment for OSA | Dr. To Kin Wang |
| 2008.193 | A Cross Sectional Study of Prevalence of Sleep Disordered Breathing in Patients on HAART in a HIV Clinic in Hong Kong | Dr To Kin Wang |
| 2013.689 | A cross over case control study using a vibration positional device for treatment of position dependent obstructive sleep apnea | Dr. TO Kin Wang |
| 2016.661 | Validation of a novel device for screening patients with symptoms of obstructive sleep apnea |
Dr. TO Kin Wang 杜建宏 |
| 2014.556 | Application of GeneXpert on bronchoscopic samples in the clinical management of patients suspicious of Tuberculosis | Dr. TO Kin Wang |
| 2016.737 | Mortality among Tuberculosis patients in Hong Kong |
Dr. TO Kin Wang 杜建宏 |
| 2009.562 | MicroRNA-mediated regulation of the multidrug resistance transporter ABCG2 | Professor To Kin Wah |
| 2012.064 | Epigenetic down-regulation of the xenobiotic transporter ACG2 - a predisposing factor for colorectal cancer development and a novel target for cancer prevention? | Professor To Kin Wah |
| 2010.398 | Novel prognostic markers for predicting response to chemotherapy in colorectal cancer | Professor To Kin Wah |
| 2011.034 | Exploiting regulation of the drug transporter ABCG2 for personalized treatment with the HMG-CoA reductase inhibitors (Statins) | Prof To Kin Wah |
| 2012.079 | Epigenetic downregulation of the xenobiotic transporter ABCG2 as a predisposing factor for diet-induced colorectal cancer development | Professor To Kin Wah |
| 2010.034 | Clinical relevance of microRNA dysregulation and DNA methylation in mediating overexpression of ABCG2 in chemo-resistant colorectal cancer | Professor To Kin Wah |
| 2011.155 | Novel prognostic biomarkers for predicting response to chemotherapy in colorectal cancer | Professor To Kin Wah |
| 2010.254 | Prognostic value of ABCG2 and its modulation by microRNAs in AML | Professor To Kin Wah |
| 2013.161 | Xenobiotic transporter ABCG2: Regulatory role in the initiation and progression of colorectal cancer | Professor To Kin Wah |
| 2014.143 | Establishment of a primary cell culture platform of human solid cancers to facilitate molecular and functional studies | Prof To Ka-Fai |
| 2014.315 | The effect of educational-based adherence intervention on adherence of inhalation therapy, disease control, quality of life and healthcare utilization among patients with chronic obstructive pulmonary disease: a randomized controlled trial, pilot study | Ms To Ka Wing |
| 2016.585 | A Multi-Center Retrospective Observational Study to Evaluate PD-L1 Protein Expression in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) |
Prof. TO Ka Fai 杜家輝教授 |
| 2017.096 | Characterization of oncogenic role of BCL3 in Epstein-Barr virus associated nasopharyngeal carcinoma |
Dr. TO Ka Fai 杜家輝 |
| 2016.231 | Target inhibition of ATM-mediated homologous recombination repair by Epstein-Barr virus miR-BARTs in nasopharyngeal carcinoma: molecular mechanisms and clinical implications |
Dr. TO Ka Fai 杜家輝 |
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