Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2013.392 | A phase Ib trial of LEE011 in combination with everolimus (RAD001) and exemestane in the treatment of postmenopausal women with hormone receptor positive HER2 negative locally advanced or metastatic breast cancer | Prof. MA Brigette Buig Yue |
| 2012.315 | A phase Ib dose escalation/randomized phase II, multicenter, open-label study of BYL719 in combination with cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma | Prof. MA Brigette Buig Yue |
| 2012.232 | A Multinational, Randomized, Double-Blind Study of Aflibercept Versus Placebo with Irinotecan/5-FU Combination (FOLFIRI) in Patients with Metastatic Colorectal Cancer (MCRC) after failure of an Oxaliplatinb Based Regimen | Dr MA Brigette Buig Yue |
| 2012.044 | A Phase 1 Dose Escalation and Pharmacokinetic Study of Alisertib (MLN8237), an Aurora A Kinase Inhibitor, in Adult East Asian Patients With Advanced Solid Tumors or Lymphomas | Dr. Ma Brigette Buig Yue |
| 2012.129 | A phase I open-label dose escalation study with expansion to assess the safety and tolerability of INC280 in patients with c-MET dependent advanced solid tumors | Prof. MA Brigette Buig Yue |
| 2013.294 | A phase Ib/II, open-label study of LJM716 in combination with BYL719 compared to taxane or irinotecan in patients with previously treated esophageal squamous cell carcinoma | Prof. MA Brigette Buig Yue |
| 2021.630 | An Open-Label, Multicenter Phase 1b/2 Study of Nanatinostat and Valganciclovir in Patients with Advanced Epstein-Barr Virus- Positive (EBV+) Solid Tumors and in Combination with Pembrolizumab in Patients with Recurrent/Metastatic Nasopharyngeal Carcinoma | Prof. MA Brigette Buig Yue |
| 2022.413 | A Randomized Open-Label Phase 3 Study of XL092 + Atezolizumab vs Regorafenib in Subjects with Metastatic Colorectal Cancer |
Prof. MA Brigette Buig Yue 馬碧如 |
| 2021.556 | A phase 2 trial of TAS 102 in recurrent/metastatic nasopharyngeal carcinoma |
Prof. MA Brigette Buig Yue 馬碧如 |
| 2024.063 | NRG-HN011: A RANDOMIZED PHASE II STUDY OF NIVOLUMAB VERSUS NIVOLUMAB AND BMS-986016 (RELATLIMAB) AS MAINTENANCE TREATMENT AFTER FIRST-LINE TREATMENT WITH PLATINUM-GEMCITABINE-NIVOLUMAB FOR PATIENTS WITH EPSTEIN-BARR VIRUS-ASSOCIATED RECURRENT/METASTATIC NASOPHARYNGEAL CARCINOMA (REMAIN) | Prof. MA Brigette Buig Yue |
| 2024.095 | A Phase 1b/2, Open-Label, Dose Escalation and Expansion Study of ADG126 in Combination with Pembrolizumab (Anti-PD-1 Antibody) in Patients with Advanced/Metastatic Solid Tumors | Prof. MA Brigette Buig Yue |
| 2022.408 | Clinical application of circulating tumour DNA (ctDNA) assay for monitoring treatment response in advanced gastrointestinal cancers (‘PROCURE-liquid’ program) | Prof. MA Brigette Buig Yue |
| 2023.455 | Multi-modal Deep Learning of Multiomics Profiles, Radiology and Histopathology Images to Advance Colorectal Cancer Classification for Precision Oncology |
Prof. MA Brigette Buig Yue 馬碧如 |
| 2023.373 | A Phase I/II, Open-Label, Multi-Center Study of ALE.C04 (anti-Claudin-1 Antibody) as a Single Agent and in Combination with Pembrolizumab (anti-PD-1 antibody) in Adult Patients with Recurrent or Metastatic (R/M) Head and Neck Squamous Cell Carcinoma | Prof. MA Brigette Buig Yue |
| 2012.191 | A randomized, double-blind, placebo-controlled phase III study of regorafenib plus best supportive care (BSC) versus placebo plus BSC in Asian subjects with metastatic colorectal cancer (CRC) who have progressed after standard therapy (CONCUR) | Prof. Ma Brigette Buig - Yue |
| 2012.192 | A pilot case-control study of second or third line treatment with cetuximab-containing chemotherapy in patients with metastatic colorectal cancer who were previously treated with cetuximab-based chemotherapy | Prof. MA Brigette |
| 2008.091 | Multi-Centre International Study of Capecitabine + Bevacizumab as Adjuvant Treatment of Colorectal Cancer (QUASAR 2) | Associate Professor Ma Brigette |
| 2009.486 | A Randomized, Multicenter, Open-label, Phase 3 Study to Compare the Efficacy and Safety of Panitumumab and Cetuximab in Subjects with Previously Treated, Wild-type KRAS, Metastatic Colorectal Cancer | Associate Professor Ma Brigette |
| 2009.222 | A phase I dose escalation, multi-center, open-label study of HSP990 administered orally in adult patients with advanced solid malignancies | Prof. Ma Brigette |
| 2009.223 | A Phase 2, Randomized, Double-blind, Placebo-controlled Study Evaluating the Safety and Efficacy of FOLFIRI in Combination With AMG 479 or AMG 655 Versus FOLFIRI for the Second-line Treatment of KRAS-mutant Metastatic Colorectal Carcinoma | Professor Ma Brigette |
| 2010.604 | Multicenter Phase II Study of MK-2206 in Previously Treated Patients with Recurrent and Metastatic Nasopharyngeal Carcinoma | Prof. MA Brigette |
| 2008.141 | A Phase II Study of GW 786034 (Pazopanib) in Advanced Thyroid Cancer | Prof. MA Brigette |
| 2012.118 | Intensification of pre-operative therapy with multi-agent chemotherapy and concurrent chemoradiotherapy prior to total mesorectal excision surgery in patients with high risk rectal cancer | Prof. MA Brigette |
| 2017.470 | Attitudes to supersized seamless trials in oncology (SUMO) - an international survey |
Prof. MA Brigette 馬碧如教授 |
| 2016.001 | Treatment of Recurrent and Advanced Metastatic Colorectal Cancer (TRACC) | Prof. MA Brigette |
| 2014.440 | A double-blind, randomised, placebo controlled Phase III study of nintedanib plus best supportive care (BSC) versus placebo plus BSC in patients with colorectal cancer refractory to standard therapies. | Prof. MA Brigette |
| 2017.110 | Developing patient derived xenograft and cell line models of cancer | Prof. MA Brigette |
| 2015.386 | Multicenter Phase II Study of Nivolumab in Previously Treated Patients with Recurrent and Metastatic Nasopharyngeal Carcinoma | Prof. MA Brigette |
| 2015.152 | Phase I/II study of aflibercept and the modified XELIRI regimen in the second-line treatment of metastatic colorectal cancer | Prof. MA Brigette |
| 2016.439 | The immunological mechanism of plasma EBV DNA clearance during radiotherapy in patients with nasopharyngeal carcinoma – a pilot study |
Prof. MA Brigette 馬碧如 |
| 2018.270 | A randomized study of neoadjuvant chemoradiotherapy with or without intensification with the FOLFOXIRI chemo-regimen for high-risk locally advanced rectal cancer |
Prof. MA Brigette 馬碧如 |
| 2019.390 | Comprehensive Precision Oncology Program at The Chinese University of Hong Kong | Prof. MA Brigette |
| 2022.243 | daNIS-3: An open-label, multi-center, phase II platform study evaluating the efficacy and safety of NIS793 and other new investigational drug combinations with standard of care (SOC) anti-cancer therapy for the second line treatment of metastatic colorectal cancer (mCRC) |
Prof. MA Brigette 馬碧如教授 |
| 2022.262 | A phase I, open-label, multi-center study of KFA115 as a single agent and in combination with pembrolizumab in patients with select advanced cancers | Prof. MA Brigette |
| 2009.402 | Elucidating predictive biomarkers of response to cetuximab in local populations with advanced colorectal cancer | Prof. MA Brigette |
| 2010.202 | Prospective evaluation of plasma EBV DNA half-life and PET-CT scanning as a new tool in assessing early response to chemotherapy in patients with advanced nasopharyngeal carcinoma | Prof. MA Brigette |
| 2012.560 | Asian Metastatic Colorectal Cancer Registry | Prof. MA Brigette |
| 2009.230 | Identifying an early indicator of drug efficacy in patients with advanced colorectal cancer - a prospective evaluation of circulating tumor cells, positron-emission tomography scan and RECIST criteria | Prof. MA Brigette |
| 2024.264 | A nurse-led lifestyle modification intervention for enhancing self-efficacy, illness perception, self-care management and steatosis grade among patients with metabolic dysfunction-associated steatotic liver disease: A pilot randomised controlled trial | Ms. MA Angel Cho Kan |
| 2023.300 | A nurse-led lifestyle modification intervention for enhancing self-efficacy, illness perception, self-care management and steatosis grade among patients with non-alcoholic fatty liver disease: A randomised controlled trial | Ms. MA Angel Cho Kan |
| 2023.693 | Perspectives on illness perception and self-management behaviours from patients with non-alcoholic fatty liver disease and healthcare professionals: An exploratory qualitative study | Ms. MA Angel Cho Kan |
| 2008.417 | An Asia Pacific Non-Randomized, Open-Label Phase II Study Evaluating the Safety and Efficacy of FOLFIRI Plus Cetuximab (Erbitux) or FOLFOX Plus Cetuximab as First-Line Therapy in Subjects with KRAS Wild-Type Metastatic Colorectal Cancer (APEC-Study) | Prof. MA Brigette |
| 2018.407 | Prospective observational cohort study to assess the ability of mechanically-ventilated patients to press buttons on a smartphone application | Miss LUNG Catherine Chi Yan |
| 2020.411 | A one–year prospective study for intrapleural pressure for thoracentesis | Dr. LUN Chung Tat |
| 2021.246 | an asthma control questionnaire in a regional hospital during covid-19 pandemic | Dr. LUN Chung Tat |
| 2021.245 | A COPD control questionnaire in a regional hospital during covid-19 pandemic | Dr. Lun Chung Tat |
| 2015.247 | Metformin-associated lactic acidosis requiring intensive care in regional hospitals in Hong Kong and predictive factors for mortality | Dr. LUN Chung Tat |
| 2012.439 | Cross Sectional Survey on Advance Care Planning Acceptance & End of Life Care Preferences among community dwelling elderly with complex medical problems and their carers | Dr LUM Chor Ming |
| 2005.264 | Psychological Distress, Quality of Life and Marital Relationship among Renal Patients Receiving Continuous Ambulatory Peritoneal Dialysis | Ms. LUK Yvonne Pik Shan |
| 2023.551 | Impact of Injury Prevention Program on Ankle stability for ballet dancers | Ms. LUK Tsz Yan |
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