Approved Study Database

Ref. No. Scientific Title Principal investigator
2006.255 A Phase III, Randomised, Double-Blind, Multi-Centre, Parallel-Group Study to Assess the Efficacy of ZD6474 (ZACTIMA Prof. Mok Tony
2006.254 A Randomised, Double-Blind, Parallel Group, Phase 3, Efficacy and Safety Study of AZD6140 Compared with Clopidogrel for Prevention of Vascular Events in Patients with Non-ST or ST Elevation Acute Coronary Syndromes (ACS) PLATO Prof. Yu Cheuk Man
2006.251 A Phase III Randomized, Placebo-Controlled Clinical Trial to Study the Safety and Efficacy of the Addition of Sitagliptin (MK-0431) in Patients with Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Combination Therapy with Metformin and A PPARy Agonist Prof. Tong Chun Yip Peter
2006.249 An Open Label Study to Assess the Efficacy of Losartan/HCTZ Combination Therapy in Patients with Essential Hypertension Who Were Inadequately Controlled on Current Antihypertensive Monotherapy Prof. Tong Chun Yip Peter
2006.242 An 8-Week, Multicenter, Randomized, Double-Blind, Parallel-Group Study to Evaluate the Efficacy and Safety of the Combination of Valsartan/HCTZ/Amlodipine Compared to Valsartan/HCTZ, Valsartan/ Amlodipine and HCTZ/Amlodipine in Patients with Moderate to Severe Hypertension Dr. Kung Kenny
2006.233 A 13-Week, Randomized, Multi-Center, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy, Safety and Tolerability of Pregabalin (150-600 MG/DAY) Using A Flexible Dosing Schedule in the Treatment of Subjects with Central Post-Stroke Pain (CPSP) Prof. Wong Ka Sing Lawrence
2006.227 Acupuncture Treatment in Adults Undergoing Diagnostic Upper Gastrointestinal Endoscopy: A Double-Blind Placebo Controlled Randomized Trial Mr. Leung Wing Wa
2006.226 A Randomized, Double Blind, Placebo-Controlled, Multicenter, Phase III Study Comparing the Activity of Paclitaxel Plus Trastuzumab Plus Lapatinib to Paclitaxel Plus Trastuzumab Plus Placebo in Women with ErbB2 Overexpressing Metastatic Breast Cancer Prof. Yeo Winnie
2006.223 A Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Safety and Efficacy of Cerebrolysin in Patients with Acute Ischemic Stroke Prof. Poon Wai Sang
2006.221 A 3-month Epidemiological Study to Establish Characteristics of Asian Patients with Acute Major Depressive Disorder Prof. Wing Yun Kwok
2006.205 An Open Label International Multi-Center Phase 2 Activity and Safety Study of SU011248 in Patients with Advanced / Metastatic Gastric Cancer Progressing or Recurring After One Prior Chemotherapy Prof. Yeo Winnie
2006.204 A Randomized, Comparative, Double-Blind, Parallel-Group, Multicenter, Monotherapy, Study of Pregabalin (Lyrica) and Lamotrigine (Lamictal) in Patients with Newly Diagnosed Partial Seizures Dr. Kwan Patrick
2006.202 A Randomized, Placebo-Controlled, Double-Blind Phase II Study of Sequential Administration of Tarceva_ (Erlotinib) or Placebo in Combination with Gemcitabine/Platinum as First-Line Treatment in Patients with Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) Prof. Mok Tony
2006.201 A Phase 3 Randomized Study to Evaluate Survival of Patients Treated with Talaporfin Sodium (LS11) and Interstitial Light Emitting Diodes (LED) as Compared to the Standard of Care Therapies in the Treatment of Unresectable Hepatocellular Carcinoma (HCC) Prof. Mok Tony
2006.197 The Impact of Postcoital Bleeding and the Effectiveness of Cryotherapy in Treatment Dr. Kong Wing Shan Grace
2006.194 A Randomized, Double-Blind, Active Comparator-Controlled, Parallel-Group Study Conducted Under In-House Blinding Conditions, to Examine the Safety, Tolerability, and Efficacy of Aprepitant for the Prevention of Postoperative Nausea and Vomiting (PONV) Prof. Gin Tony
2006.192 Use of Magnetic Imaging to Assess the Efficacy of Cap Assisted Colonoscopy in Reducing Looping and Improving Patient Acceptance for the Colonoscopy Procedure (MICstudy) Prof. Lee Yuk Tong
2006.191 Clinical Bioequivalence Study on Two Loratadine Formulations Prof. Chow S.S. Moses
2006.187 Validation of Chronic Pain Acceptance Questionnaire (CPAQ) in Cantonese-Speaking Chinese Patients Dr. Cheung Ning Michelle
2006.183 Effects of Soy Protein or Isoflavones on Glycemic Control Insulin Resistance and Cardiovascular Risks Prof. Ho Sut Ying Suzanne
2006.178 Use of Leukotriene Receptor Antagonist in the Treatment of Allergic Rhinitis Prof. Li Albert Martin
2006.170 Randomized Controlled Study on the Benefits and Safety of Bisphosphonate Treatment in Childhood Cancer Survivors Prof. Leung Ting Fan
2006.160 The Effectiveness of Domperidone and Simethicone in Bowel Preparation for Outpatient Colonoscopy: A Randomized Controlled Trial Dr. Poon Chi Ming
2006.159 A Randomized, Parallel Group, Placebo-Controlled, Double Blind Study to Assess the Safety and Tolerability of SB-681323 at 7.5mg Daily Dose for 28 days and its Effect on the Levels of Serum C-Reactive Protein (CRP) in Subjects with Rheumatoid Arthritis (RA) Prof. Li Kwok Ming Edmund
2006.158 A Randomized, Double-Blind, Placebo-Controlled, Three-Arm, Parallel-Group, Multicenter, Multinational Safety and Efficacy Trial of 300mg and 900mg of Abetimus Sodium in Systemic Lupus Erythematosus (SLE) Patients with A History of Renal Disease Prof. Li Kwok Ming Edmund
2006.157 A Multicenter, Randomized, Open Label Dose Finding Study of RO0503821 in Anemic Patients with Stage IIIB or IV Non-Small Cell Lung Cancer Receiving First Line Myelosuppressive Chemotherapy Prof. Mok Tony
2006.156 A Prospective, Randomized, Double-Blinded, Multi-Center Trial Assessing the Safety and Efficacy of Intravenous Administration Bay 12-8039 (Moxifloxacin) 400mg Every 24h Compared to Intravenous Ceftriaxone 2g Every 24h and Metronidazole 500mg Every 12h for the Treatment of Patients with Complicated Intra-Abdominal Infections Dr. Siu Wing Tai
2006.150 A Trial to Compare the Efficacy and Safety of Cilostazol with Clopidogrel in Patients with Symptomatic Intracranial Stenosis Subtitle : A Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis II (TOSS-II) Dr. Mok C.T. Vincent
2006.145 Prospective Randomized Study of Silicone Stent Intubation in Endoscopic Dacryocysto-Rhinostomy for Acquired Nasolacrimal Duct Obstruction Prof. Chong Kam Lung
2006.142 The Safety and Efficacy of A Modified Regimen of Photodynamic Therapy with Verteporfin on Chronic Central Serous Chorioretinopathy Prof. Chan Wai Man
2006.140 The Effectiveness of Monochromatic Infrared Photo Energy (MIRE) in Managing People with Diabetes Peripheral Neuropathy (DPN): A Randomized Controlled Trial Ms. Ho Yan Yan
2006.139 The Use of Intravenous Dexamethasone in Preventing Post-Thyroidectomy Throat Discomfort Following Endotracheal Intubation. A Randomized Controlled Trial Dr. TEOH Anthony Yuen Bun
2006.136 Sleep Duration, Neurohormonal Dysregulation and Obesity in Hong Kong Children and Adolescents Prof. KONG Alice PS
2006.128 A Randomized Controlled Comparison of A Multidisciplinay Pain Management Programme with A Physical Exercise Programme in Chinese Patients with Chronic Pain Dr. Chen Phoon Ping
2006.118 A Study Comparing the Efficacy of Influenza Vaccination and Sero-Conversion Rates in Different Populations in Hong Kong Prof. Hui Shu Cheong David
2006.106 Characterization of the Clinical/Biological Significance of Simian Virus 40 Infection in Childhood Acute Lymphoblastic Leukaemia Prof. Ng H.L. Margaret
2006.105 Randomized Double-Blinded Controlled Trial of Phenylephrine vs Ephedrine for Maintaining Maternal Blood Pressure During Regional Anaesthesia for Caesarean Section in Patients with Preeclampsia Prof. Ngan Kee D. Warwick
2006.102 Liraglutide Effect and Action in Diabetes (LEAD-1): Effect on Glycaemic Control After Once Daily Administration of Liraglutide in Combination With Glimepiride Versus Glimepiride Monotherapy Versus Glimepiride and Rosiglitazone Combination Therapy in Subjects with Type 2 Diabetes. A Six-Month Double-blind, Double-dummy, Randomised, Active Control, Parallel-group, Multi-Centre, Multi-National Trial Dr. Chow C.C. Francis
2006.101 Inhaled Pre-Prandial Human Insulin with the AERx_ iDMS Versus Subcutaneous Insulin Aspart in Type 2 Diabetes: A 52-week, Open-label, Multicentre, Randomized Trial Followed by 52-week Extension and 12-week Re-Randomized Extension to Investigate Safety and Efficacy Dr. Chow C.C. Francis
2006.100 Comparison of the Efficacy and Safety of Entecavir Versus Adefovir in Subjects Chronically Infected with Hepatitis B Virus and Evidence of Hepatic Decompensation Dr. Hui Josun Aric
2006.095 Reduced Factorial Design, Randomized, Double Blind Trial Comparing Combinations of Telmisartan 20 or 80 mg and Simvastatin 20 or 40 mg with Single Component Therapies in the Treatment of Hypertension and Dyslipidemia Prof. Brian Tomlinson
2006.094 Is Use of Pressurized Irrigation Method An Effective Alternative to Conventional Practice of Wound Cleansing by Swabbing? Dr. Mak So Shan
2006.090 A Phase I Study of CCI-779 in Combination with Imatinib Mesylate in Chronic Myelogenous Leukemia Dr. Lei IK Kenny
2006.082 B Cell Depletion Therapy in Rheumatoid Arthritis: An Analysis of Peripheral Blood T Cell Subsets Prof. Li Kwok Ming Edmund
2006.080 A Randomized Control Trial of 0.01% MMC 30 Second Vs 0.01% MMC 1 min as A Prophylactic Treatment to Prevent Haze Formation in LASEK Patients Prof. Lam SC Dennis
2006.057 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate the Efficacy and Safety of Saxagliptin in Combination with Glyburide in Subjects with Type 2 Diabetes Who Have Inadequate Glycemic Control on Glyburide Alone Prof. Tong C.Y. Peter
2006.040 A Randomized Controlled Trial of the Effectiveness of Traditional Chinese Style Physical Exercise (Tai Chi) in the Maintenance of Cognitive and Functional Abilities in Subjects with Mild Cognitive Impairment Prof. Lam C.W. Linda
2006.029 Prevention of Cerebrovascular and Cardiovascular Events If Ischaemic Origin with TeRutroban in Patients with a History of Ischaemic Stroke or Transient IschaeMic Attack. The PERFORM Study. An International, Randomized, Double-blind, Two Parallel Group Study Comparing Terutroban 30 mg o.d. Versus Aspirin 100mg o.d. Administered Orally for a 3-year Mean Duration (Event Driven Trial) Prof. Wong Ka Sing Lawrence
2006.027 Establishment of Baseline and Comparative Infection Rates for the Codman BACTISEAL Prof. Poon Wai Sang
2006.026 A Multi-center, Randomized, Double-blind, Parallel Group, Placebo Controlled Trial to Evaluate the Efficacy and Safety of Activated Recombinant Factor VII (rFVIIa/NovoSeven/NiaStase) in Severely Injured Trauma Patients With Bleeding Refractory to Standard Treatment Prof. Timothy H. RAINER

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