Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2023.114 | RNA m6A去甲基化酶ALKBH5对结直肠癌化疗疗效的影响及作用机制 (Targeting RNA m6A eraser ALKBH5 boosts the efficacy of chemotherapy in colorectal cancer) |
Prof. YU Jun 于君 |
| 2023.107 | Videoconferencing-based Focused Acceptance and Commitment Therapy for parents of children with special health care needs: A non-randomised controlled feasibility trial | Prof. CHONG Yuen Yu |
| 2023.108 | The effectiveness of AI-assisted bowel preparation evaluation before colonoscopy. A prospective, single-blinded, randomized-controlled trial | Prof. TANG Raymond S.Y. |
| 2023.115 | Prospective evaluation of the aetiologies, management and clinical outcomes in patients with pleural effusion | Prof. CHAN Ken Ka Pang |
| 2023.109 | Effects of a structured, family-supported, and patient-centred advance care planning on end-of-life decision making among palliative care patients and their family members: A randomized controlled trial | Dr. LO Raymond See Kit |
| 2023.110 | A pilot study comparing the clinical efficacy and bleeding risk between low dose and standard dose intrapleural tissue plasminogen activator for pleural infection | Prof. CHAN Ken Ka Pang |
| 2023.117 | Identification of novel therapeutic targets in gastric cancer with lymph node or distant metastasis: An explorative study |
Dr. CHAN Shannon Melissa 陳詩瓏 |
| 2023.111 | Body composition and growth after adenotonsillectomy for childhood obstructive sleep apnoea – a prospective longitudinal study | Prof. LI Albert Martin |
| 2023.092 | Microwave Ablation and Superheated Steam Endobronchial Treatment of Lung Primary and Oligometastatic tumours (MASS trial) |
Prof. NG Calvin Sze Hang 吳士衡 |
| 2023.093 | Conservative treatment for triggering finger - A randomized trial comparing effectiveness of thermoplastic finger blocking splints at metacarpophalangeal joint (MCPJ) and proximal interphalangeal joint (PIPJ). | Ms. SUN Hoi Ki |
| 2023.105 | The role of macrophage lipid transfer in driving immunotherapy resistance of hepatocellular carcinoma cells | Prof. CHENG Alfred Sze Lok |
| 2023.095 | Study of product of conception derived from ultrasound-guided manual vacuum aspiration |
Prof. CHUNG Jacqueline Pui Wah Pui Wah Jacqueline Chung |
| 2023.094 | Randomized Controlled Trial of Bioabsorbable Steroid Eluting Stent in Frontal Sinus Opening for Endotype II Bilateral Chronic Rhinosinusitis with Nasal Polyps in the Asian Population | Dr. YEUNG David |
| 2023.096 | Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female Cancer Patients |
Dr. CHUNG Jacqueline Pui Wah 鍾佩樺 |
| 2023.118 | Identifying genetic determinants of drug response in Chinese patients with type 2 diabetes for precision therapeutics |
Prof. MA Ronald Ching Wan 馬青雲 |
| 2023.165 | JET Enhanced Thrombectomy intervention Hong Kong Post Market Study |
Prof. TAN GuangMing 譚廣明 |
| 2023.097 | Investigating blood nucleases activity as a governing factor of molecular properties of plasma DNA | Dr. LAM Jacky Wai Kei |
| 2023.098 | A randomized trial of Danshen/Gegen in slowing cognitive decline in clinical AD and cerebral small vessel disease |
Prof. KWOK Timothy 郭志銳 |
| 2023.113 | Neural Encoding of Speech in Chinese-Learning Children | Prof. WONG Patrick Chun Man |
| 2023.104 | A Phase IIIb Single Arm, Open-label, Multicentre Study of Durvalumab and Tremelimumab as First Line Treatment in Participants with Advanced Hepatocellular Carcinoma (SIERRA) | Prof. CHAN Stephen Lam |
| 2023.103 | A Phase II, Open-Label, Multi-Drug, Multi-Centre, Master Protocol to Evaluate the Efficacy and Safety of Novel Immunomodulators as Monotherapy and in Combination with Anticancer Agents in Participants with Advanced Hepatobiliary Cancer (GEMINI-Hepatobiliary) Sub-study 1: Hepatocellular Carcinoma (HCC) | Prof. CHAN Stephen Lam |
| 2023.102 | A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Treatment of Physician’s Choice in Patients With Previously Untreated, Locally Advanced, Inoperable or Metastatic Triple-Negative Breast Cancer Whose Tumors Do Not Express PD-L1 or in Patients Previously Treated With Anti-PD-(L)1 Agents in the Early Setting Whose Tumors Do Express PD-L1 | Prof. YEO Winnie Ming Ming |
| 2023.099 | Neoadjuvant Sacituzumab Govitecan plus Pembrolizumab in Resectable Non-Small Cell Lung Cancer: an open-label, multicenter, single arm phase 2 study |
Dr. LI Siu Ching 李兆澄 |
| 2023.100 | Preventive effect of Perinatal Oral Probiotic Supplementation (POPS) on Neonatal Jaundice: A Randomized Double-Blind Placebo-Controlled Parallel-Group Superiority Clinical Trial | Dr. LAU So Ling |
| 2023.101 | Effect of IL24-expressing mesenchymal stem cells on immune system in lung cancer patients and health donors |
Dr. LI Siu Ching 李兆澄 |
| 2023.089 | Identifying novel cell subpopulation and therapeutic target for adolescent idiopathic scoliosis through combined single-nucleus and spatial transcriptomics |
Prof. LEE Wayne Yuk Wai 李郁偉 |
| 2023.088 | Manufacturing process development and validation for human mesenchymal stem cells cell bank in compliance with current Good Manufacturing Practice (cGMP) standard. |
Prof. LEE Wayne Yuk Wai 李郁偉 |
| 2023.091 | Renal, metabolic, hepatic and bone outcomes in people living with HIV and other co-morbidities receiving different anti-retroviral regimens |
Dr. LUI Grace Chung Yan 雷頌恩 |
| 2023.120 | The Hong Kong Genome Project | Prof. LO Dennis Yuk Ming |
| 2023.087 | Using inflammatory markers and microRNA to identify obese individuals at risk of nonalcoholic steatohepatitis | Prof. KONG Alice Pik Shan |
| 2023.121 | Evaluation of the effectiveness of tele-care group therapy for patient with common mental disorder | Ms. LEE Kwun Yan |
| 2023.079 | A multi-centre trial on Targeted Microwave Ablation (TMA) for localized prostate cancer using organ based tracking (OBT) navigation: The VIOLETTA trial |
Dr. CHIU Peter Ka Fung 趙家鋒 |
| 2023.085 | Association between nephrolithiasis and future cardiovascular events: a population-based analysis of patients utilizing public health systems in Hong Kong |
Prof. NG Chi Fai 吳志輝 |
| 2023.084 | Clinical Characteristics, Anticholinergic Burden, Treatment Patterns, and Drug Persistence in Patients with Overactive Bladder in Hong Kong: A Real-World Observational Study |
Prof. NG Chi Fai 吳志輝 |
| 2023.078 | Effect of Vericiguat on cardiAc remodeling in patients with heart faiLure and reduced Ejection fractioN (HFrEF): A prospective sTudy usIng NOvel echocardiographic imaging techniques (VALENTINO) |
Prof. LEE Pui Wai 李沛威 |
| 2023.077 | The SNaPP Study: Sugammadex, Neostigmine and Postoperative Pulmonary Complications | Dr. CHAN Matthew Tak Vai |
| 2023.083 | Comparing Efficacy of ICS-formoterol reliever and Salbutamol reliever in Asthma: A Retrospective Cohort Study | Mr. TSANG Shi Ming |
| 2023.081 | Uptake and Long-term Outcomes of Amblyopia and Strabismus Treatment among Chinese and Minority Ethnic Groups in Hong Kong | Dr. YAM Jason Cheuk Sing |
| 2023.080 | Trends in the Incidence and Prevalence of Complications of Myopia among Hong Kong Chinese and Minority Ethnic Groups in Hong Kong | Dr. ZHANG Xiujuan |
| 2023.086 | Dissecting the role of FNDC3B in promoting ATRA-induced apoptosis in acute myeloid leukemia |
Prof. NG Margaret Heung Ling Margaret Heung-Ling NG |
| 2023.075 | Randomized trial on Acutely Dissected Aorta Repair with Hemiarch replacement with or without stent implantation (RADAR trial) |
Prof WONG Randolph Hung Leung 黃鴻亮 |
| 2023.082 | Deciphering the branched chain amino acids (BCAA)-uridine monophosphate (UMP) axis in promoting CRC metastasis: molecular mechanisms and therapeutic implications |
Dr. WONG Chi Chun Chi Chun Wong |
| 2023.074 | A pilot randomized controlled trial of MRI-informed high-frequency transcranial random noise stimulation (hf-tRNS) for sleep disturbance and cognitive dysfunction in mild vascular cognitive impairment | Dr. LU Hanna |
| 2023.073 | Effectiveness evaluation of paper-based cognitive training in reducing cognitive decline for outpatients with early stage of dementia | Mr. HO Tak Wai |
| 2023.069 | A Randomized, Open-label, Phase 3 Trial of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in Treatment-naïve Subjects with Advanced or Metastatic PD-L1 High (TPS ≥50%) Non-small Cell Lung Cancer Without Actionable Genomic Alterations (TROPION-Lung08) | Dr. LOONG Herbert Ho Fung |
| 2023.106 | Time-to-event machine learning model for predicating malignant transformation of oral lichenoid conditions: a multicenter cohort study | Dr. CHAN Amy Bik Wan |
| 2023.072 | Sealing the gaps: Lactobacillus spp. mediated mitigation of insulin resistance-induced intestinal epithelium dysfunction and modulation of carbapenem resistant Klebsiella pneumoniae infection in an in vivo model | Prof. IP Margaret |
| 2023.076 | A post discharged phone-supported program have positive effect on physical activity of individuals with schizophrenia |
Ms. HO Cassandra Wing Hang 何泳恒 |
| 2023.071 | Epidemiology of Klebsiella pneumoniae by whole-genome sequencing | Prof. IP Margaret |
| 2023.119 | Electroacupuncture for Post-COVID Neurocognitive Symptoms: Sham Controlled Randomized Trial | Prof. CHUNG Vincent Chi Ho |
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